Health Benefits Of Pterostilbene
Evidence regarded as substantial has gone onto recommend that pterostilbene offers a number of therapeutic and neurological properties over a range of different human diseases which include hematologic, neurological, metabolic and cardiovascular disorders. Additional benefits associated with pterostilbene are reports derived from preclinical trials, where pterostilbene was discovered to be a powerful anticancer-agent in various malignancies.
Pterostilbene is a compound that is naturally derived, found mainly in blueberries as well as PM (Pterocarpus marsupium) heartwood. The daily amount of pterostilbene consumption will vary according to the intake of dietary fruit, with an estimated pterostilbene content varying from 99ng to 520ng/gram per a blueberry, dependent on the berry type ingested. You would need to eat 10,000 blueberries for a therapeutic dose of pterostilbene.
Pterostilbene has a much higher absorption than resveratrol
Pterostilbene is similar in structure to resveratrol, which is one of the compounds that can be found in a drink such as red wine, which is associated with comparable anticarcinogenic, anti-inflammatory, and antioxidant properties. However, pterostilbene showed increased bioavailability in association to 2 methoxy groups which results in an increased oral and lipophilic absorption. In a number of animal studies conducted, it was discovered that pterostilbene had 80% bioavailability in comparison to 20% for resveratrol which makes it more advantageous in the form of therapeutic agents.
Benefits of Pterostilbene in the prevention and treatment of disease
The extensive benefits associated with pterostilbene for the prevention and treatment of human diseases, is mainly attributed to the anticarcinogenic, anti-inflammatory and antioxidant properties which leads to improvements in the functioning of the normal cells and the inhibition of the malignant cells. The treatments with PM and blueberry extract in disease models that are similar have yielded similar results, which is suggested to be linked to the underlying mechanisms and antioxidant activity of pterostilbene. Evidence has shown that pterostilbene is able to decrease OS (oxidative stress) as well as production of ROS (reactive oxygen species) like superoxide anion and hydrogen peroxide which are both implicated in initiating pathogenesis of a number of disease processes.
